Perspectives of the Use of Neoadjuvant Therapy in the Management of Locally Advanced and Locally Recurrent Colon Cancer: A Bi‐National Survey of Colorectal Surgeons

The survey reveals a paradigm shift among colorectal surgeons in Australia and New Zealand toward incorporating neoadjuvant therapies for managing LACC and locally recurrent colon cancer. While upfront resection remains standard of care, there is increasing adoption of neoadjuvant strategies to downstage tumors and potentially improve oncological outcomes. Further high-quality evidence and randomized controlled trials are warranted to refine patient selection and optimize treatment protocols in these challenging clinical scenarios.

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Publication Details

Journal
Asia-Pacific Journal of Clinical Oncology
Published
2025-10-13
DOI
https://doi.org/10.1111/ajco.70035
Primary Topic
Colorectal Cancer Surgical Treatments
Type
article
Field-Weighted Citation Impact
0.00
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article

Perspectives of the Use of Neoadjuvant Therapy in the Management of Locally Advanced and Locally Recurrent Colon Cancer: A Bi‐National Survey of Colorectal Surgeons

Vignesh Narasimhan, Alexander G. Heriot, Satish K. Warrier, Rathin Gosavi
Asia-Pacific Journal of Clinical Oncology
Colorectal Cancer Surgical Treatments
article

Perspectives of the Use of Neoadjuvant Therapy in the Management of Locally Advanced and Locally Recurrent Colon Cancer: A Bi‐National Survey of Colorectal Surgeons

Vignesh Narasimhan, Alexander G. Heriot, Satish K. Warrier, Rathin Gosavi
article en

Abstract

The survey reveals a paradigm shift among colorectal surgeons in Australia and New Zealand toward incorporating neoadjuvant therapies for managing LACC and locally recurrent colon cancer. While upfront resection remains standard of care, there is increasing adoption of neoadjuvant strategies to downstage tumors and potentially improve oncological outcomes. Further high-quality evidence and randomized controlled trials are warranted to refine patient selection and optimize treatment protocols in these challenging clinical scenarios.

Asia-Pacific Journal of Clinical Oncology
Peter MacCallum Cancer Centre (AU), Monash Health (AU)
Openalex Percentile: Top 61%
Colorectal Cancer Surgical Treatments
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