The utility of CXCL13 and circulating CXCR5+ T cell detection in the diagnosis of systemic lupus erythematosus associated nephritis
Serum CXCL13 has high accuracy in the diagnosis of SLE, and circulating CXCR5<sup>+</sup> T cells may serve as a novel biomarker for the diagnosis of SLE and LN, which might complement the poor performance of serum CXCL13 in the diagnostic efficacy of LN.
Authors
- Yunlong Yang (ORCID: https://orcid.org/0000-0002-0684-7515)
- Yu Liu (ORCID: https://orcid.org/0000-0001-6729-5702)
- Ting Liu (ORCID: https://orcid.org/0000-0003-1816-5551)
- Hui Lü (ORCID: https://orcid.org/0000-0002-8225-8739)
- Siyu Tan (ORCID: https://orcid.org/0000-0002-5202-3103)
- Meng-ke Huang
Institutions
- Sichuan University (CN)
- West China Second University Hospital of Sichuan University (CN)
- Xi'an Honghui Hospital (CN)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2025-10-14
- DOI
- https://doi.org/10.3389/fimmu.2025.1657350
- Primary Topic
- Systemic Lupus Erythematosus Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Natural Science Foundation of Sichuan Province