The impact of high-intensity interval training on cerebrovascular function in the APP/PS1 mice
HIIT ameliorates cognitive function and reduces hallmark AD pathology. This positive effect is potentially mediated through cerebral microangiogenesis, cerebrovascular function regulation, and hypoxic metabolism. HIIT represents a promising non-pharmacological strategy for targeting multiple aspects of AD pathophysiology.
Authors
- Jingyun Hu (ORCID: https://orcid.org/0000-0001-8912-7857)
- Ming Cai (ORCID: https://orcid.org/0000-0001-6469-3967)
- Qi Wang (ORCID: https://orcid.org/0000-0002-9239-1998)
- Lei Zhu (ORCID: https://orcid.org/0000-0003-1685-7968)
- Zhe Lu (ORCID: https://orcid.org/0000-0001-6877-9426)
- Teng Zhai
Institutions
- Qufu Normal University (CN)
- Shanghai University of Medicine and Health Sciences (CN)
- Pudong New Area People's Hospital (CN)
Publication Details
- Journal
- Frontiers in Aging
- Published
- 2025-10-14
- DOI
- https://doi.org/10.3389/fragi.2025.1647628
- Primary Topic
- Apelin-related biomedical research
- Type
- article
- Field-Weighted Citation Impact
- 0.00