Aging and activity patterns: actigraphy evidence from NHANES studies

Aging is associated with shifts in sleep-wake cycles and activity patterns, reflecting biological and behavioral adaptations. These findings highlight the importance of personalized interventions to support optimal activity and sleep alignment across the lifespan. Insights from actigraphy data can inform public health strategies and clinical approaches to aging-related changes in physical activity and circadian regulation. These age-stratified, interpretable "dynamical phenotypes" provide observables to calibrate and validate systems-level models of sleep-wake regulation and behavior-physiology coupling, supporting hypothesis generation and intervention design in systems biology.