Determinants of <scp>HBsAg</scp> Loss After Nucleos(t)ide Discontinuation in a Prospective Cohort of <scp>HBeAg</scp> ‐Negative Caucasian Patients
NA withdrawal results in functional cure rates exceeding 25%, particularly in patients with long-term antiviral treatment and low qHBsAg levels. Combining qHBsAg levels at EOT and at 3 months accurately stratifies patients according to the probability of HBsAg loss. Close monitoring to detect the need for treatment re-introduction is mandatory.
Authors
- Sabela Lens (ORCID: https://orcid.org/0000-0003-4900-411X)
- Clara Amiama Roig (ORCID: https://orcid.org/0000-0002-6327-010X)
- Sergio Rodríguez‐Tajes (ORCID: https://orcid.org/0000-0002-3189-7557)
- Mercedes Rodríguez (ORCID: https://orcid.org/0000-0002-7258-301X)
- Mireia Miquel (ORCID: https://orcid.org/0000-0003-4566-4962)
- Xavier Forns (ORCID: https://orcid.org/0000-0002-8188-1764)
- J.A. Carrión (ORCID: https://orcid.org/0000-0001-7191-6081)
- Marı́a Buti (ORCID: https://orcid.org/0000-0002-0732-3078)
- Javier García‐Samaniego (ORCID: https://orcid.org/0000-0002-9974-0855)
- Anna Pocurull (ORCID: https://orcid.org/0000-0002-1970-1822)
- Teresa Broquetas (ORCID: https://orcid.org/0000-0002-5935-3076)
- Elena Hoyas
- Queralt Herms (ORCID: https://orcid.org/0009-0005-6459-5052)
- Manuel Rodríguez (ORCID: https://orcid.org/0000-0001-5763-7668)
- Emilio Suárez (ORCID: https://orcid.org/0009-0003-4053-9895)
Institutions
- Universitat de Vic - Universitat Central de Catalunya (ES)
- Universitat Autònoma de Barcelona (ES)
- Hospital Universitario La Paz (ES)
- Instituto de Salud Carlos III (ES)
- Centro de Investigación Biomédica en Red (ES)
- Hospital Clínic de Barcelona (ES)
- Vall d'Hebron Hospital Universitari (ES)
- Hospital Del Mar (ES)
- Hospital Universitario Central de Asturias (ES)
- Institute of Research and Innovation Parc Tauli (ES)
- Hospital Universitario de Valme (ES)
- Universidad Autónoma de Madrid (ES)
- Universitat de Barcelona (ES)
Publication Details
- Journal
- Liver International
- Published
- 2025-10-13
- DOI
- https://doi.org/10.1111/liv.70371
- Primary Topic
- Hepatitis B Virus Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00