The efficacy of varying doses of venetoclax combined with azacitidine for newly diagnosed adult acute myeloid leukemia in real-world settings: a single-center retrospective analysis

These findings suggest that while both dosing strategies may yield comparable initial responses, long-term outcomes could be adversely influenced by dose reduction, and the 2024 ELN risk classification is more suitable for adult patients with ndAML receiving a reduced-dose regimen of venetoclax and azacitidine.

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Publication Details

Journal
Hematology
Published
2025-10-14
DOI
https://doi.org/10.1080/16078454.2025.2571248
Primary Topic
Acute Myeloid Leukemia Research
Type
article
Field-Weighted Citation Impact
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article

The efficacy of varying doses of venetoclax combined with azacitidine for newly diagnosed adult acute myeloid leukemia in real-world settings: a single-center retrospective analysis

Xi Yang, Yingxin Sun, Tianzhi Wang, Yang Li et al.
Hematology
Acute Myeloid Leukemia Research
article

The efficacy of varying doses of venetoclax combined with azacitidine for newly diagnosed adult acute myeloid leukemia in real-world settings: a single-center retrospective analysis

Xi Yang, Yingxin Sun, Tianzhi Wang, Yang Li, Yanjie Mao, Yaping Zhang, Hong Liu, Yanan Wu, Yifeng Cai
article en

Abstract

These findings suggest that while both dosing strategies may yield comparable initial responses, long-term outcomes could be adversely influenced by dose reduction, and the 2024 ELN risk classification is more suitable for adult patients with ndAML receiving a reduced-dose regimen of venetoclax and azacitidine.

HematologyVol. 30(1)
Nantong University (CN), Soochow University (CN), Affiliated Hospital of Nantong University (CN), First Affiliated Hospital of Soochow University (CN)
Openalex Percentile: Top 63%
Acute Myeloid Leukemia Research
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