KIF1Bβ suppresses hepatocellular carcinoma by transporting and secreting FBLN5 to attenuate the integrin pathway

Our findings shed light on the genetic and molecular mechanisms of the HCC-associated susceptibility locus at 1p36.22 and provide potential new strategies for the treatment of HCC.

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Publication Details

Journal
Gut
Published
2025-10-13
DOI
https://doi.org/10.1136/gutjnl-2025-336230
Primary Topic
Microtubule and mitosis dynamics
Type
article
Field-Weighted Citation Impact
0.00
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article

KIF1Bβ suppresses hepatocellular carcinoma by transporting and secreting FBLN5 to attenuate the integrin pathway

Junjie Wu, Rui Guo, Rong Liang, Guangming Zhou et al.
Gut
Microtubule and mitosis dynamics
article

KIF1Bβ suppresses hepatocellular carcinoma by transporting and secreting FBLN5 to attenuate the integrin pathway

Junjie Wu, Rui Guo, Rong Liang, Guangming Zhou, Xiaoyu Hu, Yifei Qiu, K. D. Hao, Tao Zeng, Chenning Yang, Pengbo Cao, Ruofan Li, Yuanfeng Li, Jiazhou Ye, Fuchu He, Yuting Wang, Ying Zhang, Han Yan, Qiming Wang, Jiao Wang, Yahui Wang, Chang Gao, Furong Cheng, Jinwen Zhang, Song Liao, Peipei Shi, Hongbo Yan
article en

Abstract

Our findings shed light on the genetic and molecular mechanisms of the HCC-associated susceptibility locus at 1p36.22 and provide potential new strategies for the treatment of HCC.

Gut
Guangxi Medical University (CN), Second Military Medical University (CN), Anhui Medical University (CN), Nanjing Health and Health Commission (CN), People's Liberation Army No. 150 Hospital (CN), Changhai Hospital (CN), Beijing Proteome Research Center (CN), Tumor Hospital of Guangxi Medical University (CN), Hebei University (CN)
Openalex Percentile: Top 69%
Microtubule and mitosis dynamics
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