Tectochrysin alleviates high-glucose-induced retinal pigment epithelial cell injury through Nrf2/HO-1 activation
The findings demonstrate that tectochrysin protects ARPE-19 cells from HG-induced injury by inhibiting apoptosis, ferroptosis and EMT while activating Nrf2/HO-1 signaling, suggesting its potential as a therapeutic agent for diabetic retinopathy.
Authors
- Bingbing Jiang (ORCID: https://orcid.org/0000-0003-2217-6202)
- Wei Shan Li (ORCID: https://orcid.org/0000-0001-7458-2590)
- Shuang Wang (ORCID: https://orcid.org/0000-0003-3817-392X)
- Chenyu Zhang (ORCID: https://orcid.org/0000-0002-9799-8772)
- Yuan Sui (ORCID: https://orcid.org/0000-0001-6424-2648)
Institutions
- Shenyang 242 Hospital (CN)
Publication Details
- Journal
- Folia Histochemica et Cytobiologica
- Published
- 2025-10-14
- DOI
- https://doi.org/10.5603/fhc.107923
- Citations
- 1
- Primary Topic
- Retinal Diseases and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 1.71
Funders
- Health Commission of Heilongjiang Province