ITRAQ and PRM-based quantitative saliva proteomics in gastric cancer: biomarker discovery
Our findings demonstrate that salivary proteins, particularly S100A8, S100A9, CST4, and CST5, hold significant potential as non-invasive biomarkers for gastric cancer detection. These results provide new insights into saliva-based diagnostics and highlight the importance of cross-comparison with tissue and blood expression profiles.
Authors
- J. E. Mo
- Jieren Liu (ORCID: https://orcid.org/0009-0002-2102-3001)
- Yuanzhe Cai
- Hao Chi (ORCID: https://orcid.org/0000-0002-5210-0770)
- Kun Luo (ORCID: https://orcid.org/0000-0002-5754-0222)
- Zhengzhi Wu (ORCID: https://orcid.org/0000-0002-8819-609X)
- Feijuan Huang
- Zaid Chachar (ORCID: https://orcid.org/0000-0001-8038-4996)
- Chenhao Zhang (ORCID: https://orcid.org/0000-0002-2696-2860)
- Y.-t. Mao (ORCID: https://orcid.org/0009-0009-8444-2458)
- Zhanyan Liu
- Guohui Li (ORCID: https://orcid.org/0000-0003-0033-3895)
- Runyu Wen (ORCID: https://orcid.org/0009-0006-1253-1193)
Institutions
- Hunan University of Traditional Chinese Medicine (CN)
- Longgang Central Hospital (CN)
- First Affiliated Hospital of Hunan University of Traditional Chinese Medicine (CN)
- Chinese University of Hong Kong, Shenzhen (CN)
- Hunan Academy of Traditional Chinese Medicine (CN)
- Shenzhen Technology University (CN)
- Shenzhen Second People's Hospital (CN)
Publication Details
- Journal
- Frontiers in Molecular Biosciences
- Published
- 2025-10-14
- DOI
- https://doi.org/10.3389/fmolb.2025.1640508
- Citations
- 2
- Primary Topic
- Salivary Gland Disorders and Functions
- Type
- article
- Field-Weighted Citation Impact
- 2.33