Machine Learning Identifies Predictors of Amniotic Membrane Graft Failure in Neurotrophic Keratitis

Systemic immunosuppression, repeated AMTs, and prior ocular surgery are key predictors of AMT failure in NK. Combining regression models, clustering, and machine learning provides a robust framework for risk stratification. These findings support the development of personalized monitoring and treatment strategies to improve surgical outcomes in NK.

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Publication Details

Journal
Ophthalmology and Therapy
Published
2025-10-14
DOI
https://doi.org/10.1007/s40123-025-01259-z
Primary Topic
Ocular Surface and Contact Lens
Type
article
Field-Weighted Citation Impact
0.00
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article

Machine Learning Identifies Predictors of Amniotic Membrane Graft Failure in Neurotrophic Keratitis

Vincent Daïen, Frédéric Michon, Des Fernandes, Hannah Crowdy
Ophthalmology and Therapy
Ocular Surface and Contact Lens
article

Machine Learning Identifies Predictors of Amniotic Membrane Graft Failure in Neurotrophic Keratitis

Vincent Daïen, Frédéric Michon, Des Fernandes, Hannah Crowdy
article en

Abstract

Systemic immunosuppression, repeated AMTs, and prior ocular surgery are key predictors of AMT failure in NK. Combining regression models, clustering, and machine learning provides a robust framework for risk stratification. These findings support the development of personalized monitoring and treatment strategies to improve surgical outcomes in NK.

Ophthalmology and TherapyVol. 14(12)
The University of Sydney (AU), Inserm (FR), Université de Montpellier (FR), Hôpital Gui de Chauliac (FR), Institute for Neurosciences of Montpellier (FR)
Openalex Percentile: Top 61%
Ocular Surface and Contact Lens
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