Unsupervised Lung Tumor Segmentation in CT Images Using K-Means and Hierarchical Clustering: A Comparative Analysis Toward Early Detection

Background: Lung cancer is among a top cause of cancer-related fatalities worldwide, and timely, accurate detection is essential to improving patient survival rates. Examining CT scans manually takes significant time and is susceptible to observer variation, creating the need for automated detection systems. Methods Used: This study presents an unsupervised segmentation framework for lung tumours in CT images using K-means and Hierarchical Clustering. The process involves grayscale conversion, noise filtering, contrast enhancement, clustering-based segmentation, and morphological post-processing. Results Achieved: Performance indicators such as the Dice Similarity Coefficient (DSC) and the Jaccard Index, tumor area, perimeter, and circularity show that hierarchical clustering provides more accurate and morphologically consistent results, while K-means is computationally faster but less precise. Concluding Remarks: The findings support the use of unsupervised clustering as an effective annotation-free approach for tumor segmentation and pave the way for future research into hybrid and deep learning-based models that can enhance segmentation accuracy and clinical applicability.

Publication Details

Journal
Iconic Research and Engineering Journals
Published
2025-10-11
DOI
https://doi.org/10.64388/irev9i4-1711184-9501
Primary Topic
Radiomics and Machine Learning in Medical Imaging
Type
article
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article

Unsupervised Lung Tumor Segmentation in CT Images Using K-Means and Hierarchical Clustering: A Comparative Analysis Toward Early Detection

Iconic Research and Engineering Journals
Radiomics and Machine Learning in Medical Imaging
article

Unsupervised Lung Tumor Segmentation in CT Images Using K-Means and Hierarchical Clustering: A Comparative Analysis Toward Early Detection

article en

Abstract

Background: Lung cancer is among a top cause of cancer-related fatalities worldwide, and timely, accurate detection is essential to improving patient survival rates. Examining CT scans manually takes significant time and is susceptible to observer variation, creating the need for automated detection systems. Methods Used: This study presents an unsupervised segmentation framework for lung tumours in CT images using K-means and Hierarchical Clustering. The process involves grayscale conversion, noise filtering, contrast enhancement, clustering-based segmentation, and morphological post-processing. Results Achieved: Performance indicators such as the Dice Similarity Coefficient (DSC) and the Jaccard Index, tumor area, perimeter, and circularity show that hierarchical clustering provides more accurate and morphologically consistent results, while K-means is computationally faster but less precise. Concluding Remarks: The findings support the use of unsupervised clustering as an effective annotation-free approach for tumor segmentation and pave the way for future research into hybrid and deep learning-based models that can enhance segmentation accuracy and clinical applicability.

Iconic Research and Engineering JournalsVol. 9(4)
Openalex Percentile: Top 57%
Radiomics and Machine Learning in Medical Imaging
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Unsupervised Lung Tumor Segmentation in CT Images Using K-Means and Hierarchical Clustering: A Comparative Analysis Toward Early Detection · Iconic Research and Engineering Journals (2025) | TGRS Research Map | TGRS