Proteomics and β-hydroxybutyrylome reveal the novel mechanisms underlying fluconazole resistance in <i>Candida albicans</i>
Fluconazole-resistant <i>C. albicans</i> poses a growing threat. This study links reduced β-hydroxybutyrylation to fluconazole resistance and highlights post-translational modifications as potential therapeutic targets.
Authors
- Qiao‐Li Lv
- Yi Jin (ORCID: https://orcid.org/0000-0003-4335-6691)
- Bin Xu (ORCID: https://orcid.org/0000-0002-8279-4304)
- Lı Zhang (ORCID: https://orcid.org/0000-0003-0467-0290)
- Weihua Pan (ORCID: https://orcid.org/0000-0001-7381-5188)
- Kaiyuan Liu (ORCID: https://orcid.org/0000-0002-3404-2802)
- Liuyang Cai
Institutions
- Shanghai Jiao Tong University (CN)
- Jiangxi Provincial Cancer Hospital (CN)
- Shanghai First People's Hospital (CN)
Publication Details
- Journal
- Future Microbiology
- Published
- 2025-09-22
- DOI
- https://doi.org/10.1080/17460913.2025.2572207
- Primary Topic
- Antifungal resistance and susceptibility
- Type
- article
- Field-Weighted Citation Impact
- 0.00