Age and sex influence diurnal memory oscillations, circadian rhythmicity, and Per1 expression
Diurnal oscillations in spatial memory are sex- and age-dependent in mice. Per1 learning-induced expression matches diurnal memory patterns. Circadian rhythm patterns are sex- and age-dependent in mice. Young females show good memory across the diurnal cycle. Diurnal memory oscillations reemerge in old female mice.
Authors
- Janine L. Kwapis (ORCID: https://orcid.org/0000-0002-2349-8601)
- Chad W. Smies (ORCID: https://orcid.org/0000-0003-0507-1441)
- Lauren Bellfy (ORCID: https://orcid.org/0000-0001-9846-7319)
- Alicia R. Bernhardt
- Megan J. von Abo
- Gretchen C. Pifer
- Marilyn Jackson
- A.S. Perumal
Institutions
- Pennsylvania State University (US)
Publication Details
- Journal
- Biology of Sex Differences
- Published
- 2025-10-14
- DOI
- https://doi.org/10.1186/s13293-025-00756-x
- Primary Topic
- Circadian rhythm and melatonin
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Brain Research Foundation
- McKnight Foundation
- Evelyn F. McKnight Brain Research Foundation
- National Institutes of Health