AXL activation governs the liver microenvironment to protect ischemia–reperfusion injury by suppressing NLRP3 inflammasome
This study not only elucidates how AXL reprograms macrophages but also suggests a therapeutic target for mitigating liver I/R injury.
Authors
- Qi Fang (ORCID: https://orcid.org/0000-0002-9762-2687)
- Ruixin Zhang (ORCID: https://orcid.org/0000-0002-2463-4839)
- Jian Du (ORCID: https://orcid.org/0000-0001-5010-7859)
- Mengting Zhan (ORCID: https://orcid.org/0000-0001-5467-3022)
- Weizhi Wang (ORCID: https://orcid.org/0000-0002-7310-4068)
- Haijian Cai
- Yaru Xu (ORCID: https://orcid.org/0000-0002-8397-311X)
- Lixia Zha
- Xingyun Liu
- Qi Yan (ORCID: https://orcid.org/0000-0002-5236-9673)
- Xiaolu Zhang (ORCID: https://orcid.org/0000-0002-5821-228X)
- Lei Yao (ORCID: https://orcid.org/0000-0001-9996-4149)
- Liu Deng (ORCID: https://orcid.org/0000-0002-1392-6828)
- Lijian Chen (ORCID: https://orcid.org/0000-0003-0627-1138)
Institutions
- Anhui University (CN)
- Anhui Medical University (CN)
- First Affiliated Hospital of Anhui Medical University (CN)
Publication Details
- Journal
- Cellular & Molecular Biology Letters
- Published
- 2025-10-14
- DOI
- https://doi.org/10.1186/s11658-025-00795-7
- Citations
- 3
- Primary Topic
- Phagocytosis and Immune Regulation
- Type
- article
- Field-Weighted Citation Impact
- 2.39