Development, validation and visualization of risk prediction model for postoperative shivering in patients undergoing video-assisted thoracoscopic lobectomy: a real-world retrospective study

To develop, validate, and visualize a risk prediction model for postoperative shivering in patients undergoing video-assisted thoracoscopic (VATS) lobectomy, addressing the lack of individualized tools for this high-risk population. This retrospective study analyzed 530 patients undergoing VATS lobectomy from a tertiary hospital in Wuhan (January 2022-December 2023). The data were randomly divided into training set and validation set at a ratio of 7∶3. Patients were stratified into postoperative shivering (n = 198) and non-postoperative shivering (n = 332) groups based on Bedside Shivering Assessment Scale (BSAS) criteria. Logistic regression identified independent risk factors, and a nomograph was developed. Model performance was evaluated using the area under the receiver operating characteristic curve (AUC), calibration curves, Hosmer-Lemeshow test, and decision curve analysis (DCA). An online visualization tool was created for clinical implementation. Postoperative shivering occurred in 198 of 530 patients undergoing VATS lobectomy (37.36%). The logistic regression analysis identified age < 60 years, intraoperative hypothermia, delayed anesthesia recovery, absence of postoperative analgesia, operation duration > 180 min and lower preoperative temperature as significant risk factors for postoperative shivering (P < 0.05). The resulting nomograph demonstrated strong discrimination with AUCs of 0.847 (95%CI: 0.809-0.885) in the training cohort (n = 424) and 0.836 (95%CI: 0.747-0.925) in validation (n = 106), while calibration curves and the Hosmer-Lemeshow test (χ<sup>2</sup> = 13.123, P = 0.108) confirmed model reliability. DCA demonstrated clinical utility across threshold probabilities of 0.20-0.98. In order to promote clinical implementation, deployment of the visualization tools online ( https://shivering.shinyapps.io/dynnomapp/ ), which supports dynamic risk assessment. This study established the first risk prediction model for postoperative shivering in patients undergoing VATS lobectomy, integrating six perioperative variables into a clinically applicable nomograph and online tool. The model facilitates identification of high-risk patients, enabling targeted interventions to mitigate shivering-related complications.

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Journal
Scientific Reports
Published
2025-10-14
DOI
https://doi.org/10.1038/s41598-025-19879-7
Citations
1
Primary Topic
Thermal Regulation in Medicine
Type
article
Field-Weighted Citation Impact
1.55
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article

Development, validation and visualization of risk prediction model for postoperative shivering in patients undergoing video-assisted thoracoscopic lobectomy: a real-world retrospective study

Jun S. Liu, Qing Yan, Juan Hu, Jing Zhang et al.
1 citations
Scientific Reports
Thermal Regulation in Medicine
1.55
article

Development, validation and visualization of risk prediction model for postoperative shivering in patients undergoing video-assisted thoracoscopic lobectomy: a real-world retrospective study

Jun S. Liu, Qing Yan, Juan Hu, Jing Zhang, Li Gui, Jinhong Li, Qiang Li, Zhineng Cheng, Fuhai Xia, Rui Chen
article en
1 citations

Abstract

To develop, validate, and visualize a risk prediction model for postoperative shivering in patients undergoing video-assisted thoracoscopic (VATS) lobectomy, addressing the lack of individualized tools for this high-risk population. This retrospective study analyzed 530 patients undergoing VATS lobectomy from a tertiary hospital in Wuhan (January 2022-December 2023). The data were randomly divided into training set and validation set at a ratio of 7∶3. Patients were stratified into postoperative shivering (n = 198) and non-postoperative shivering (n = 332) groups based on Bedside Shivering Assessment Scale (BSAS) criteria. Logistic regression identified independent risk factors, and a nomograph was developed. Model performance was evaluated using the area under the receiver operating characteristic curve (AUC), calibration curves, Hosmer-Lemeshow test, and decision curve analysis (DCA). An online visualization tool was created for clinical implementation. Postoperative shivering occurred in 198 of 530 patients undergoing VATS lobectomy (37.36%). The logistic regression analysis identified age < 60 years, intraoperative hypothermia, delayed anesthesia recovery, absence of postoperative analgesia, operation duration > 180 min and lower preoperative temperature as significant risk factors for postoperative shivering (P < 0.05). The resulting nomograph demonstrated strong discrimination with AUCs of 0.847 (95%CI: 0.809-0.885) in the training cohort (n = 424) and 0.836 (95%CI: 0.747-0.925) in validation (n = 106), while calibration curves and the Hosmer-Lemeshow test (χ<sup>2</sup> = 13.123, P = 0.108) confirmed model reliability. DCA demonstrated clinical utility across threshold probabilities of 0.20-0.98. In order to promote clinical implementation, deployment of the visualization tools online ( https://shivering.shinyapps.io/dynnomapp/ ), which supports dynamic risk assessment. This study established the first risk prediction model for postoperative shivering in patients undergoing VATS lobectomy, integrating six perioperative variables into a clinically applicable nomograph and online tool. The model facilitates identification of high-risk patients, enabling targeted interventions to mitigate shivering-related complications.

Scientific ReportsVol. 15(1)
Huazhong University of Science and Technology (CN)
Openalex Percentile: Top 14%
Thermal Regulation in Medicine
1.55
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