Mapping the global intellectual landscape of inflammatory tumor microenvironment in colorectal cancer pathogenesis and prognostic research since this century
This study preliminary visualize the association of inflammatory TME with CRC through bibliometric analysis. The immunomodulatory mechanisms in IBD-associated carcinogenesis, NF-κB-mediated TME remodeling in tumor progression, and CRC patient stratification and precision therapeutics were three hotspots for future research endeavors on the inflammatory TME in CRC research.
Authors
- Can Lv (ORCID: https://orcid.org/0000-0003-4252-3822)
- Junyan He (ORCID: https://orcid.org/0000-0002-8334-3484)
- Xuan Zheng (ORCID: https://orcid.org/0000-0002-1145-7167)
- Yushu Zhu (ORCID: https://orcid.org/0009-0000-4289-0046)
- Feihu Yan (ORCID: https://orcid.org/0000-0003-4227-0757)
- Hui Mu (ORCID: https://orcid.org/0000-0001-7246-569X)
- Li Bai (ORCID: https://orcid.org/0000-0002-7169-1334)
- Zhi‐Wei Liu (ORCID: https://orcid.org/0000-0003-3005-1792)
- Jiaojiao Chen (ORCID: https://orcid.org/0000-0002-7420-4052)
- Zhaoming Wang (ORCID: https://orcid.org/0000-0001-7556-3869)
- Yi Zeng (ORCID: https://orcid.org/0000-0001-9144-8414)
- Enda Yu (ORCID: https://orcid.org/0000-0003-4631-610X)
- Xiaoyu Tu
Institutions
- Second Military Medical University (CN)
- Shanghai University of Traditional Chinese Medicine (CN)
- Shanghai Changzheng Hospital (CN)
- Changhai Hospital (CN)
- Shanghai First People's Hospital (CN)
Publication Details
- Journal
- Discover Oncology
- Published
- 2025-10-14
- DOI
- https://doi.org/10.1007/s12672-025-03524-w
- Primary Topic
- Cancer Immunotherapy and Biomarkers
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Natural Science Foundation of Shanghai
- Shanghai Municipal Health Commission
- National Natural Science Foundation of China
- Changhai Hospital of Shanghai