Preclinical Validation of a Patient-Specific Patch-Planning Workflow for Congenital Cardiovascular Reconstruction
Preclinical evaluation of a patch-planning workflow demonstrated accurate reconstruction of BPA stenosis. Incorporation of material properties is essential to achieve targeted reconstructed dimensions under physiological conditions. Model credibility assessment and in vitro validation of more complex patient-specific anatomy will precede prospective clinical trials.
Authors
- Dominic P. Recco (ORCID: https://orcid.org/0000-0003-2306-6443)
- Peter E. Hammer (ORCID: https://orcid.org/0000-0003-4151-2777)
- Jocelyn Davee
- Kenneth I. Aycock (ORCID: https://orcid.org/0000-0003-1257-5111)
- Nicholas E. Kneier
- Jiang Yao (ORCID: https://orcid.org/0000-0002-8479-2564)
- Brent A. Craven (ORCID: https://orcid.org/0000-0001-8474-4856)
- Shannen B. Kizilski (ORCID: https://orcid.org/0000-0003-2447-1969)
- Pras Pathmanathan (ORCID: https://orcid.org/0000-0003-2111-6689)
- Patrick D. Earley
- David M. Hoganson
- A Masterson
Institutions
- Boston Children's Hospital (US)
- United States Food and Drug Administration (US)
- Center for Devices and Radiological Health (US)
- Harvard University (US)
- Baylor University (US)
- Office of Science (US)
- Dassault Systèmes (United States) (US)
- Dassault Systèmes (France) (FR)
Publication Details
- Journal
- Annals of Biomedical Engineering
- Published
- 2025-10-14
- DOI
- https://doi.org/10.1007/s10439-025-03870-4
- Citations
- 1
- Primary Topic
- Congenital Heart Disease Studies
- Type
- article
- Field-Weighted Citation Impact
- 1.35
Funders
- Additional Ventures
- National Institutes of Health