Widespread Progressive Telangiectasia in a 54-Year-Old Caucasian Male

Telangiectasia macularis multiplex acquisita (TMMA) is a rarely reported cutaneous vascular disorder characterised by widespread telangiectatic macules, most commonly affecting middle-aged adults. It has been reported predominantly in East Asian populations, particularly in Chinese and Korean cohorts. TMMA has also been observed in association with systemic conditions, including chronic liver disease, hypertension, type 2 diabetes mellitus, and dyslipidaemia. We present a case of a 54-year-old Caucasian male with progressive, symmetrical telangiectatic lesions affecting the face, upper limbs, and trunk. He reported chronic elevated alcohol intake and a history of significant sun exposure. Laboratory investigations were unremarkable. Histopathological examination confirmed superficial dermal telangiectasia without mast cell proliferation, consistent with TMMA. The patient was referred to a photodermatology specialist and managed conservatively with lifestyle modification. This case contributes to the limited English-language literature on TMMA and underscores the importance of distinguishing it from mimics such as telangiectasia macularis eruptiva perstans (TMEP).

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Journal
Cureus
Published
2025-10-14
DOI
https://doi.org/10.7759/cureus.94588
Primary Topic
Dermatologic Treatments and Research
Type
article
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article

Widespread Progressive Telangiectasia in a 54-Year-Old Caucasian Male

Ayesha Imran, Elena Koleva, Hayder N Alhameedi, G. Morley et al.
Cureus
Dermatologic Treatments and Research
article

Widespread Progressive Telangiectasia in a 54-Year-Old Caucasian Male

Ayesha Imran, Elena Koleva, Hayder N Alhameedi, G. Morley, Samuel Audet, Layla Ali, Stefani Kikina
article en

Abstract

Telangiectasia macularis multiplex acquisita (TMMA) is a rarely reported cutaneous vascular disorder characterised by widespread telangiectatic macules, most commonly affecting middle-aged adults. It has been reported predominantly in East Asian populations, particularly in Chinese and Korean cohorts. TMMA has also been observed in association with systemic conditions, including chronic liver disease, hypertension, type 2 diabetes mellitus, and dyslipidaemia. We present a case of a 54-year-old Caucasian male with progressive, symmetrical telangiectatic lesions affecting the face, upper limbs, and trunk. He reported chronic elevated alcohol intake and a history of significant sun exposure. Laboratory investigations were unremarkable. Histopathological examination confirmed superficial dermal telangiectasia without mast cell proliferation, consistent with TMMA. The patient was referred to a photodermatology specialist and managed conservatively with lifestyle modification. This case contributes to the limited English-language literature on TMMA and underscores the importance of distinguishing it from mimics such as telangiectasia macularis eruptiva perstans (TMEP).

CureusVol. 17(10)
University College Hospital (GB), Royal Berkshire Hospital (GB), University Hospital Southampton NHS Foundation Trust (GB), Antrim Area Hospital (GB), Queen Elizabeth Hospital (GB), Basildon Hospital (GB), University College London (GB)
Openalex Percentile: Top 51%
Dermatologic Treatments and Research
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Widespread Progressive Telangiectasia in a 54-Year-Old Caucasian Male — Ayesha Imran, Elena Koleva, et al. · Cureus (2025) | TGRS Research Map | TGRS