Ifinatamab Deruxtecan in Patients With Extensive-Stage Small Cell Lung Cancer: Primary Analysis of the Phase II IDeate-Lung01 Trial
I-DXd 12 mg/kg once every 3 weeks showed promising efficacy in patients with previously treated ES-SCLC. The observed safety profile was consistent with previous reports, with no new safety signals identified.
Authors
- J. Godard
- Tetsuya Sakai (ORCID: https://orcid.org/0000-0001-5884-2735)
- Myung‐Ju Ahn (ORCID: https://orcid.org/0000-0002-5740-9654)
- Hidetoshi Hayashi (ORCID: https://orcid.org/0000-0001-8787-5587)
- Yu Jung Kim (ORCID: https://orcid.org/0000-0002-5037-0523)
- Pedro Rocha (ORCID: https://orcid.org/0000-0003-3221-7354)
- Melissa L. Johnson (ORCID: https://orcid.org/0000-0001-9874-1314)
- Charles M. Rudin (ORCID: https://orcid.org/0000-0001-5204-3465)
- Mei Tang
- Luis Paz‐Ares (ORCID: https://orcid.org/0000-0002-1947-3364)
- Christine L. Hann (ORCID: https://orcid.org/0000-0002-1467-5557)
- Makoto Nishio (ORCID: https://orcid.org/0000-0003-4969-4165)
- Haichuan Hu (ORCID: https://orcid.org/0000-0003-3436-290X)
- Nicolas M Girard (ORCID: https://orcid.org/0000-0001-9909-2299)
- Jasmeet Singh (ORCID: https://orcid.org/0000-0003-2318-4546)
- Meng Qian (ORCID: https://orcid.org/0000-0002-5659-1159)
Institutions
- Merck & Co., Inc., Rahway, NJ, USA (United States) (US)
- Memorial Sloan Kettering Cancer Center (US)
- Daiichi Sankyo (Germany) (DE)
- Samsung Medical Center (KR)
- Seoul National University Bundang Hospital (KR)
- Sarah Cannon (US)
- Hospital Universitario 12 De Octubre (ES)
- Vall d'Hebron Hospital Universitari (ES)
- The Cancer Institute Hospital (JP)
- National Cancer Center Hospital East (JP)
- Daiichi Sankyo (United States) (US)
- Sidney Kimmel Comprehensive Cancer Center (US)
- Japanese Foundation For Cancer Research (JP)
- Vall d'Hebron Institute of Oncology (ES)
- Institut Curie (FR)
- Sungkyunkwan University (KR)
- Kindai University (JP)
Publication Details
- Journal
- Journal of Clinical Oncology
- Published
- 2025-10-14
- DOI
- https://doi.org/10.1200/jco-25-02142
- Citations
- 4
- Primary Topic
- Lung Cancer Research Studies
- Type
- article
- Field-Weighted Citation Impact
- 4.18