Two new alkaloids identified from herb <i>Delphinium trichophorum</i> French, a famous Tibetan drug “Gebu Dilu”

A new benzamide derivative alkaloid (<b>1</b>) and a new hetisine-type diterpenoid alkaloid (<b>2</b>) were isolated from <i>D. trichophorum</i> Franch with fourteen known alkaloids compounds (<b>3</b>∼<b>16</b>, including twelve hetisine-type diterpenoid alkaloids), in which three compounds were discovered firstly from genus <i>Delphinium</i> (<b>10</b>, <b>15</b>, <b>16</b>) and three compounds were discovered firstly from species <i>D. -trichophorum</i> (<b>7</b>, <b>9</b>, <b>11</b>). Their structures were elucidated by -extensive spectroscopic analyses, including 1D NMR, 2D NMR and ESI-MS/HR ESI-MS techniques, along with their anti-inflammatory activities were evaluated by measuring NO production in LPS-stimulated RAW264.7 cells.