Experimental acute muscle pain and itch induce similar inhibitory effects on corticospinal excitability

Opposite to the hypothesis, acute, experimental pain and itch induced similar corticospinal inhibition, suggesting a comparable effect on the motor output of the affected limb. This study found that the effects of acute pain and itch showed similar inhibition on bilateral corticospinal tract excitability.

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Publication Details

Journal
PAIN Reports
Published
2025-10-14
DOI
https://doi.org/10.1097/pr9.0000000000001341
Primary Topic
Pain Mechanisms and Treatments
Type
article
Field-Weighted Citation Impact
0.00
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article

Experimental acute muscle pain and itch induce similar inhibitory effects on corticospinal excitability

Lars Arendt‐Nielsen, Jesper Elberling, Silvia Lo Vecchio, Enrico De Martino et al.
PAIN Reports
Pain Mechanisms and Treatments
article

Experimental acute muscle pain and itch induce similar inhibitory effects on corticospinal excitability

Lars Arendt‐Nielsen, Jesper Elberling, Silvia Lo Vecchio, Enrico De Martino, Bolette Harritsø Winther, Johanne Bagger Graugaard, Hannah Grønlund Jespersen
article en

Abstract

Opposite to the hypothesis, acute, experimental pain and itch induced similar corticospinal inhibition, suggesting a comparable effect on the motor output of the affected limb. This study found that the effects of acute pain and itch showed similar inhibition on bilateral corticospinal tract excitability.

PAIN ReportsVol. 10(6)
University of Copenhagen (DK), Steno Diabetes Centers (DK), Aalborg University Hospital (DK), Gentofte Hospital (DK), Mech-Sense (DK), Aalborg University (DK)
Openalex Percentile: Top 64%
Pain Mechanisms and Treatments
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Experimental acute muscle pain and itch induce similar inhibitory effects on corticospinal excitability — Lars Arendt‐Nielsen, Jesper Elberling, et al. · PAIN Reports (2025) | TGRS Research Map | TGRS