BioClock—optimizing Bright Light Therapy for adults with depression: a study protocol for a multicenter randomized clinical trial on treatment strategies, response predictors, and chronobiological and neurobiological mechanisms

Authors

Willem van der Does (ORCID: https://orcid.org/0000-0002-9753-2454)
Machteld Marcelis (ORCID: https://orcid.org/0000-0003-0045-9244)
Luc J. M. Schlangen (ORCID: https://orcid.org/0000-0002-8424-7240)
Oana Georgiana Rus-Oswald (ORCID: https://orcid.org/0000-0003-2952-5583)
Yvonne de Kort (ORCID: https://orcid.org/0000-0002-8127-397X)
Niki Antypa (ORCID: https://orcid.org/0000-0001-9343-8842)
Claudia J.P. Simons (ORCID: https://orcid.org/0000-0002-7637-3589)
Priscilla P. Oomen (ORCID: https://orcid.org/0000-0001-8430-0905)
Marijke C. M. Gordijn (ORCID: https://orcid.org/0000-0001-9521-8085)
E. Visser (ORCID: https://orcid.org/0000-0002-6177-155X)
T. Seetsen

Institutions

Leiden University (NL)
Radboud University Nijmegen (NL)
University of Groningen (NL)
University of Applied Sciences Leiden (NL)
Maastricht University (NL)
Eindhoven University of Technology (NL)

Publication Details

Journal: Trials
Published: 2025-10-14
DOI: https://doi.org/10.1186/s13063-025-08984-7
Citations: 1
Primary Topic: Circadian rhythm and melatonin
Type: article
Field-Weighted Citation Impact: 0.91

Funders

Nederlandse Organisatie voor Wetenschappelijk Onderzoek

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article

BioClock—optimizing Bright Light Therapy for adults with depression: a study protocol for a multicenter randomized clinical trial on treatment strategies, response predictors, and chronobiological and neurobiological mechanisms

Willem van der Does, Machteld Marcelis, Luc J. M. Schlangen, Oana Georgiana Rus-Oswald et al.

Oct 14, 2025

1 citations

Trials

Circadian rhythm and melatonin

0.91

article

BioClock—optimizing Bright Light Therapy for adults with depression: a study protocol for a multicenter randomized clinical trial on treatment strategies, response predictors, and chronobiological and neurobiological mechanisms

Willem van der Does, Machteld Marcelis, Luc J. M. Schlangen, Oana Georgiana Rus-Oswald, Yvonne de Kort, Niki Antypa, Claudia J.P. Simons, Priscilla P. Oomen, Marijke C. M. Gordijn, E. Visser, T. Seetsen

October 14, 2025article en

1 citations

Abstract

No abstract available for this paper.

TrialsVol. 26(1)

Leiden University (NL), Radboud University Nijmegen (NL), University of Groningen (NL), University of Applied Sciences Leiden (NL), Maastricht University (NL), Eindhoven University of Technology (NL)

Nederlandse Organisatie voor Wetenschappelijk Onderzoek

Openalex Percentile: Top 22%

Circadian rhythm and melatonin

0.91

DOI Open Access PDF OpenAlex

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