BDNF genotype associated with changes in cortical thickness, severity of symptoms, and cognitive impairments in mild traumatic brain injury
These findings suggest that BDNF polymorphisms in mTBI patients are associated with brain structural changes and may serve as valuable biomarkers for identifying individuals at risk for long-term clinical symptoms and cognitive impairment.
Authors
- Zhiqi Lee (ORCID: https://orcid.org/0000-0002-9658-5255)
- Xiang Zhang (ORCID: https://orcid.org/0000-0002-8790-0313)
- Nengrui Guo
- Yizhen Pan (ORCID: https://orcid.org/0000-0002-2473-2287)
- Lijun Bai (ORCID: https://orcid.org/0000-0002-9090-9335)
- Tao Liu (ORCID: https://orcid.org/0000-0002-0506-3356)
- Xuan Li (ORCID: https://orcid.org/0000-0002-8941-2575)
- Tingting Wu (ORCID: https://orcid.org/0000-0002-0812-2059)
- Lei Shi (ORCID: https://orcid.org/0000-0002-5359-7862)
- Haonan Zhang (ORCID: https://orcid.org/0000-0002-4239-6141)
- Jue Zhang (ORCID: https://orcid.org/0000-0003-3200-4594)
- Jierui Ding
- Zhuonan Wang (ORCID: https://orcid.org/0000-0002-5745-4340)
- Jie Yuan (ORCID: https://orcid.org/0009-0006-1975-2853)
Institutions
- Shanghai University of Traditional Chinese Medicine (CN)
- First Affiliated Hospital of Xi'an Jiaotong University (CN)
- Shuguang Hospital (CN)
- Xi'an Jiaotong University (CN)
Publication Details
- Journal
- Molecular Brain
- Published
- 2025-10-14
- DOI
- https://doi.org/10.1186/s13041-025-01239-1
- Primary Topic
- Traumatic Brain Injury Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China