Optimal image-derived input function models for multi-parameter analysis and acceptably reduced acquisition time in [18F]F-FAPI-42 PET total-body dynamic imaging for lung cancer
The RVIF model appears to be more suitable than the DAIF model for quantifying kinetic parameters in [<sup>18</sup>F]F-FAPI-42 PET dynamic imaging of lung cancer, with an acceptable shortened acquisition time of 26 min.
Authors
- Kemin Zhou (ORCID: https://orcid.org/0000-0002-4279-2515)
- Jiahao Xie (ORCID: https://orcid.org/0000-0002-8306-2973)
- Yanjiang Han (ORCID: https://orcid.org/0000-0002-1987-503X)
- Hubing Wu (ORCID: https://orcid.org/0000-0002-7546-5430)
- Yanchao Huang
- Ganghua Tang (ORCID: https://orcid.org/0000-0002-2712-253X)
- Penghui Sun (ORCID: https://orcid.org/0000-0002-7247-6185)
- Dazhi Shi
- Lijuan Wang (ORCID: https://orcid.org/0000-0002-8445-2391)
- Ying Tian (ORCID: https://orcid.org/0000-0001-7957-3220)
Institutions
- Nanfang Hospital (CN)
- Southern Medical University (CN)
Publication Details
- Journal
- EJNMMI Physics
- Published
- 2025-10-14
- DOI
- https://doi.org/10.1186/s40658-025-00802-y
- Citations
- 1
- Primary Topic
- Peptidase Inhibition and Analysis
- Type
- article
- Field-Weighted Citation Impact
- 1.05
Funders
- National Natural Science Foundation of China
- Basic and Applied Basic Research Foundation of Guangdong Province