Integrated profiling of semen microbiota and metabolome reveals dysregulation in primary idiopathic male infertility
This integrated analysis reveals distinct dysbiosis of the seminal microbiota and metabolic disruptions in idiopathic male infertility, offering novel insights into its mechanisms and biomarker discovery.
Authors
- Dajian Qiu
- Yang Xian
- Lijuan Ying (ORCID: https://orcid.org/0000-0002-6279-2168)
- Wenrui Zhao
- Yelin Jia (ORCID: https://orcid.org/0000-0002-1345-1412)
- Tingting Yang (ORCID: https://orcid.org/0000-0001-9927-3057)
- Jinyan Xu (ORCID: https://orcid.org/0000-0003-4265-7150)
- Fuping Li (ORCID: https://orcid.org/0000-0001-5183-4214)
- Xuefeng Luo (ORCID: https://orcid.org/0000-0002-3992-5866)
- Yuan Liu (ORCID: https://orcid.org/0000-0001-5899-0201)
- Shasha Liu (ORCID: https://orcid.org/0000-0003-1937-1314)
- Luo Chen (ORCID: https://orcid.org/0000-0003-0727-9545)
- Qinqin Wu
- Xiaohong Luo
- Zhenmi Liu (ORCID: https://orcid.org/0000-0003-0840-1071)
- Huan Yao (ORCID: https://orcid.org/0000-0001-5076-2650)
- Run Tian
- Бо Лю (ORCID: https://orcid.org/0000-0003-3045-628X)
- Xiao Xiao (ORCID: https://orcid.org/0000-0003-1816-775X)
Institutions
- Sichuan University (CN)
- West China Second University Hospital of Sichuan University (CN)
- West China Hospital of Sichuan University (CN)
- Maternal and Child Health Hospital of Sichuan Province (CN)
Publication Details
- Journal
- Journal of Translational Medicine
- Published
- 2025-10-14
- DOI
- https://doi.org/10.1186/s12967-025-07139-1
- Citations
- 1
- Primary Topic
- Sperm and Testicular Function
- Type
- article
- Field-Weighted Citation Impact
- 1.70
Funders
- Health Commission of Sichuan Province