Antibiotics and Surgical Site Infection in Expander-Based Breast Reconstruction Trial (ASSERT)
This multi-institutional RCT did not definitively demonstrate that a single preoperative dose of antibiotics is not inferior to a 7-day postoperative antibiotic regimen in preventing SSI in immediate TE-BR; there was also no evidence to support that the 7-day regimen was significantly better. As this represents one of the largest multi-institutional study of its kind, these results have practice-management considerations.
Authors
- Adeyiza Olutoyin Momoh (ORCID: https://orcid.org/0009-0005-5266-417X)
- Katie Sommers
- Kaiyu Zhu (ORCID: https://orcid.org/0000-0001-7364-1923)
- Jonlin Chen (ORCID: https://orcid.org/0000-0001-6803-0933)
- Sarah Block (ORCID: https://orcid.org/0000-0002-2487-9377)
- Geoffrey E. Hespe (ORCID: https://orcid.org/0000-0003-1961-7484)
- Kanad Ghosh
- Sarah Bishop (ORCID: https://orcid.org/0000-0002-4145-8865)
- Iman Khan (ORCID: https://orcid.org/0009-0006-1139-7703)
- L. Deruyter
- Gedge D. Rosson (ORCID: https://orcid.org/0000-0003-1817-9443)
- Michele A. Manahan
- Rafael Felix P. Tiongco (ORCID: https://orcid.org/0000-0001-9213-5081)
- Brett Thomas Phillips (ORCID: https://orcid.org/0000-0001-9765-2600)
- Barry J. Doyle (ORCID: https://orcid.org/0000-0003-4923-2796)
- Jeffrey H. Kozlow
- Carisa M. Cooney
- Kristen P. Broderick (ORCID: https://orcid.org/0000-0002-2591-4146)
- Rebecca Knackstedt (ORCID: https://orcid.org/0000-0003-0961-4378)
- Lily R. Mundy (ORCID: https://orcid.org/0000-0003-4821-1424)
- Gina T. McClure
- Kirstie Morley
- Joseph S. Puthumana (ORCID: https://orcid.org/0000-0001-8481-1983)
- Jessica Hsu (ORCID: https://orcid.org/0000-0001-9348-0792)
- Scott Thomas Hollenbeck (ORCID: https://orcid.org/0000-0003-3065-4892)
- Christine H. Rohde (ORCID: https://orcid.org/0000-0001-9005-7753)
- Jennifer B. Hamill (ORCID: https://orcid.org/0000-0002-1887-6401)
- Rena Atayeva (ORCID: https://orcid.org/0009-0006-0108-464X)
- Salih Colakoğlu (ORCID: https://orcid.org/0000-0002-8747-0616)
- Matthew J. Heron (ORCID: https://orcid.org/0000-0002-7578-8053)
- Summer E. Hanson (ORCID: https://orcid.org/0000-0002-4106-9819)
- Damon S. Cooney (ORCID: https://orcid.org/0000-0002-2786-287X)
- Theodore A. Kung (ORCID: https://orcid.org/0000-0002-0642-5558)
- Geoffroy C. Sisk
- Jennifer Gallagher
- William Rodriguez (ORCID: https://orcid.org/0000-0002-9949-0550)
- Jackson Hanna
- Paige L. Myers
- Danielle Sim
- Cheng-Shiun Leu
- Risal Djohan
- Rothy Rim
- Rachel Paskert
Institutions
- Cleveland Clinic (US)
- Johns Hopkins University (US)
- University of Michigan (US)
- Columbia University Irving Medical Center (US)
- Johns Hopkins Medicine (US)
- University of Chicago Medical Center (US)
- Plastic Surgery Foundation (US)
- Duke Medical Center (US)
- Oncoceutics (United States) (US)
- Columbia University (US)
Publication Details
- Journal
- Annals of Surgical Oncology
- Published
- 2025-10-14
- DOI
- https://doi.org/10.1245/s10434-025-18472-6
- Citations
- 1
- Primary Topic
- Breast Implant and Reconstruction
- Type
- article
- Field-Weighted Citation Impact
- 2.01