Progressive clonic slowing predicts severity of respiratory dysfunction and prolonged postictal immobility in tonic–clonic seizures
This study found that during some convulsive seizures, the jerking movements of the body slow down gradually before the seizure ends. This pattern, called progressive clonic slowing, was linked to more severe breathing problems and longer periods of immobility afterward. Recognizing this pattern may help doctors identify seizures that carry higher risks and guide efforts to prevent sudden death in people with epilepsy.
Authors
- Thienan John Phamnguyen (ORCID: https://orcid.org/0000-0001-9532-7003)
- David C. Reutens (ORCID: https://orcid.org/0000-0002-1652-9369)
- Stephen J. Walsh (ORCID: https://orcid.org/0000-0002-0505-648X)
- Viktor Vegh (ORCID: https://orcid.org/0000-0002-4310-1421)
- Fred Tremayne
- Lata Vadlamudi (ORCID: https://orcid.org/0000-0002-8742-0125)
- Xiaohua Chen (ORCID: https://orcid.org/0000-0002-9338-1695)
- Cecilie Margaret Lander (ORCID: https://orcid.org/0000-0002-3548-9550)
- Alice‐Ann Sullivan
Institutions
- Mater Health Services (AU)
- Queensland University of Technology (AU)
- The University of Queensland (AU)
- Royal Brisbane and Women's Hospital (AU)
- ARC Centre of Excellence for Plant Success in Nature and Agriculture (AU)
- Mater Adult Hospital (AU)
Publication Details
- Journal
- Epilepsia Open
- Published
- 2025-10-14
- DOI
- https://doi.org/10.1002/epi4.70161
- Primary Topic
- Epilepsy research and treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- University of Queensland