Addressing common biases in the evaluation of lifetime alcohol consumption patterns and dementia risk: the EPIC-Spain dementia cohort
In this large prospective cohort with over 1,100 dementia cases and long-term follow-up, alcohol consumption was not significantly associated with dementia risk. These findings challenge the notion of a protective effect of moderate drinking and warrant continued investigation using methodologically rigorous approaches to clarify the role of alcohol dose, timing, and pattern on dementia risk.
Authors
- Olatz Mokoroa (ORCID: https://orcid.org/0000-0003-3831-6089)
- María Encarnación Andreu-Reinón (ORCID: https://orcid.org/0000-0003-4086-7963)
- Marcela Guevara (ORCID: https://orcid.org/0000-0001-9242-6364)
- Sandra M. Colorado‐Yohar (ORCID: https://orcid.org/0000-0002-6700-0780)
- Dafina Petrova (ORCID: https://orcid.org/0000-0002-0346-6776)
- Marta Crous‐Bou (ORCID: https://orcid.org/0000-0003-1493-4288)
- José María Huerta (ORCID: https://orcid.org/0000-0002-9637-3869)
- Mikel Tainta (ORCID: https://orcid.org/0000-0003-0624-1211)
- Alba Gasque (ORCID: https://orcid.org/0000-0001-6236-4887)
- María José Sánchez
- María Dolores Chirlaque
Institutions
- Basque Government (ES)
- Universidad de Antioquia (CO)
- Instituto de Salud Pública de Navarra (ES)
- Institut d'Investigació Biomédica de Bellvitge (ES)
- Ministry of Health (ES)
- Biogipuzkoa Health Research Institute (ES)
- Institut Català d'Oncologia (ES)
- Navarre Institute of Health Research (ES)
- Instituto de Investigación Biosanitaria de Granada (ES)
- Hospital Universitario Virgen de las Nieves (ES)
- Osakidetza (ES)
- Onkologikoa (ES)
- Instituto Murciano de Investigación Biosanitaria (ES)
- Hospital Universitario Virgen de la Arrixaca (ES)
- Centro de Investigación Biomédica en Red de Epidemiología y Salud Pública (ES)
- Andalusian School of Public Health (ES)
- Universidad de Murcia (ES)
Publication Details
- Journal
- Frontiers in Nutrition
- Published
- 2025-10-14
- DOI
- https://doi.org/10.3389/fnut.2025.1671047
- Primary Topic
- Alcohol Consumption and Health Effects
- Type
- article
- Field-Weighted Citation Impact
- 0.00