miR-1287-5p suppresses proliferation, migration, invasion and promotes apoptosis in gastric cancer cells through targeting LAMTOR3
This current study found that miR-1287-5p suppressed GC cells proliferation, migration, and invasion while increasing apoptosis by decreasing LAMTOR3 expression. This revealed that miR-1287-5p may function as a plausible therapeutic target or biomarker for GC.
Authors
- Jinjia Zhang
- Rongying Wang (ORCID: https://orcid.org/0009-0008-3307-2621)
- Min Zhang (ORCID: https://orcid.org/0000-0001-7055-6790)
- Jinxin Zhang (ORCID: https://orcid.org/0000-0002-6311-4174)
- Wenwen Zhao (ORCID: https://orcid.org/0000-0002-7438-6300)
- Huadong Wu (ORCID: https://orcid.org/0000-0003-3603-4360)
Institutions
- Hebei Medical University (CN)
- Second Hospital of Hebei Medical University (CN)
- Xingtai People's Hospital (CN)
Publication Details
- Journal
- World Journal of Surgical Oncology
- Published
- 2025-10-14
- DOI
- https://doi.org/10.1186/s12957-025-04032-5
- Primary Topic
- Circular RNAs in diseases
- Type
- article
- Field-Weighted Citation Impact
- 0.00