Protective and therapeutic effects of hexagonal boron nitride against hydrogen peroxide-induced oxidative damage in human gingival fibroblasts
Within the limitations of this in vitro study, hBN was found to enhance cell viability under H₂O₂-induced oxidative stress in HGF cells. These findings suggest a potential role for hBN in modulating antioxidant responses and supporting periodontal healing processes. However, their clinical relevance remains uncertain. Therefore, further mechanistic studies and clinical investigations are required to validate the potential adjunctive role of hBN in the prevention and treatment of periodontal diseases.
Authors
- Mehmet Alı Sungur (ORCID: https://orcid.org/0000-0001-5380-0819)
- Neşe Ayşit (ORCID: https://orcid.org/0000-0002-4243-9092)
- Cansu Kara Öztabağ
- Akif Hakan Kurt (ORCID: https://orcid.org/0000-0003-2940-3172)
- Yapıncak Göncü (ORCID: https://orcid.org/0000-0002-8602-9765)
- Bilge Meraci (ORCID: https://orcid.org/0000-0001-9848-0927)
- Isil Yalcin Bilke (ORCID: https://orcid.org/0000-0001-9037-9373)
Institutions
- Istanbul Medipol University (TR)
- Eskişehir Osmangazi University (TR)
- Düzce Üniversitesi (TR)
- Bolu Abant İzzet Baysal University (TR)
Publication Details
- Journal
- BMC Oral Health
- Published
- 2025-10-14
- DOI
- https://doi.org/10.1186/s12903-025-07010-1
- Primary Topic
- Oral and gingival health research
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Eskişehir Teknik Üniversitesi
- Abant Izzet Baysal Üniversitesi