Kawasaki Disease Survivor With Progressive Coronary Vascular Remodeling and Ischemic Cardiomyopathy: A Case of a Heart Transplantation Recipient

Kawasaki disease presents dilation and occlusion of one or more coronary arteries in patients with early to late phases. Here we present the case of a 41-year-old Japanese male who underwent heart transplantation due to Kawasaki disease which was diagnosed at 3 years of age. The coronary arteries of the explanted heart showed pathological variations such as vascular remodeling, including aneurysm, intimal thickening, recanalization of occludes parts, and neovascularization of all vessels, especially developed vasa vasorum in the distal segments. Continuous vascular remodeling of coronary arteries may have developed progressive left ventricular dysfunction during the very late phase of Kawasaki disease.