Transcriptomic analysis in peripheral blood mononuclear cells from hyper and hypo weight-loss responders
This study provides novel evidence on how gene expression may contribute to the variability in weight loss responses, resulting in a hyper- or hypo-response to caloric restriction. The upregulation of GSPT1 and the downregulation of genes involved in collagen-related pathways are proposed as key molecular mechanisms influencing the hypo-response during caloric restriction.
Authors
- Iván Delgado‐Enciso (ORCID: https://orcid.org/0000-0001-9848-862X)
- Diana A. Vela‐Vásquez (ORCID: https://orcid.org/0000-0001-6330-4149)
- Ana María Sifuentes‐Rincón (ORCID: https://orcid.org/0000-0002-3867-9886)
Institutions
- Instituto Politécnico Nacional (MX)
- Universidad de Colima (MX)
Publication Details
- Journal
- Genes & Nutrition
- Published
- 2025-10-14
- DOI
- https://doi.org/10.1186/s12263-025-00783-8
- Citations
- 1
- Primary Topic
- Adipose Tissue and Metabolism
- Type
- article
- Field-Weighted Citation Impact
- 1.16
Funders
- Consejo Nacional de Ciencia y Tecnología