Circulating metabolites and bladder cancer: a Mendelian randomization and multi-omics study
This work explored causal links between specific circulating metabolites and BLCA, uncovering functionally significant metabolic pathways through combined metabolomic and Transcriptomic studies. The identified correlations between metabolites and genes provided a new understanding of BLCA metabolomics and laid the groundwork for the development of tailored metabolic treatments.
Authors
- Zhe Chang (ORCID: https://orcid.org/0000-0002-9720-803X)
- Zhigang Hu (ORCID: https://orcid.org/0000-0002-5265-3535)
- Siyu Chen (ORCID: https://orcid.org/0000-0001-5745-5071)
- Li Wang (ORCID: https://orcid.org/0000-0001-7692-5067)
- Yang Li (ORCID: https://orcid.org/0000-0001-9612-2704)
- Jian Wang
Institutions
- Xuzhou Medical College (CN)
- Affiliated Hospital of Xuzhou Medical College (CN)
- Lanzhou University Second Hospital (CN)
- Lanzhou University (CN)
Publication Details
- Journal
- Discover Oncology
- Published
- 2025-10-14
- DOI
- https://doi.org/10.1007/s12672-025-03709-3
- Primary Topic
- Bladder and Urothelial Cancer Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China