Integrated machine learning-based establishment of a prognostic model in multicenter cohorts for acute myeloid leukemia
This study highlights the clinical value of leukemic cell-specific genes and presents MLAPS as a robust prognostic tool. CD69 may serve as a potential therapeutic target in AML.
Authors
- Xiaoyi Xu (ORCID: https://orcid.org/0000-0001-8432-6291)
- Yan Lin (ORCID: https://orcid.org/0000-0003-3802-2988)
- Hui Yu (ORCID: https://orcid.org/0000-0003-2288-4671)
- Ming-Cheng Liu (ORCID: https://orcid.org/0009-0007-7697-2534)
Institutions
- Chinese Academy of Medical Sciences & Peking Union Medical College (CN)
- Tianjin First Center Hospital (CN)
- Institute of Hematology & Blood Diseases Hospital (CN)
- Tianjin Medical University (CN)
Publication Details
- Journal
- Frontiers in Oncology
- Published
- 2025-10-14
- DOI
- https://doi.org/10.3389/fonc.2025.1649594
- Primary Topic
- Acute Myeloid Leukemia Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China