A chromosome-level genome assembly of the Chinese herbal medicine Chelidonium majus

Chelidonium majus is a herbaceous plant of significant medicinal value, which has been widely distributed in Europe, Asia, and Northern Africa. However, its genome remains uncharacterized. Herein, we present a high-quality chromosome-scale genome for C. majus with a size of 1.06 Gb, and 91.21% of the sequences anchored onto 6 chromosomes, comprising 1,520 contigs with an N50 of 106.65 Mb. The genome is predicted to contain 25,203 protein-coding genes, with 98.2% have been functional annotated. The completeness of the genome is highlighted by a BUSCO score of 97.6%. This high-quality genome assembly provides a vital resource for future gene screening, drug discovery, and pharmacological exploration in C. majus.

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Journal
Scientific Data
Published
2025-10-14
DOI
https://doi.org/10.1038/s41597-025-05928-3
Primary Topic
Berberine and alkaloids research
Type
article
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article

A chromosome-level genome assembly of the Chinese herbal medicine Chelidonium majus

Xialian Bu, Ai-Long Zheng, Jing Chen, Jian Zhu et al.
Scientific Data
Berberine and alkaloids research
article

A chromosome-level genome assembly of the Chinese herbal medicine Chelidonium majus

Xialian Bu, Ai-Long Zheng, Jing Chen, Jian Zhu, Huantao Qu, Lei Huang, Xianqi Peng, Weijie Sun, Chen Niu, Chiping Kong, Yu Zhao, Jiayun Yao, Xiaohong Huang
article en

Abstract

Chelidonium majus is a herbaceous plant of significant medicinal value, which has been widely distributed in Europe, Asia, and Northern Africa. However, its genome remains uncharacterized. Herein, we present a high-quality chromosome-scale genome for C. majus with a size of 1.06 Gb, and 91.21% of the sequences anchored onto 6 chromosomes, comprising 1,520 contigs with an N50 of 106.65 Mb. The genome is predicted to contain 25,203 protein-coding genes, with 98.2% have been functional annotated. The completeness of the genome is highlighted by a BUSCO score of 97.6%. This high-quality genome assembly provides a vital resource for future gene screening, drug discovery, and pharmacological exploration in C. majus.

Scientific DataVol. 12(1)
China Three Gorges Corporation (China) (CN), Jiaxing University (CN), Zhejiang Institute of Freshwater Fisheries (CN), Jiaxing Vocational Technical College (CN), Ministry of Agriculture and Rural Affairs (CN)
Openalex Percentile: Top 68%
Berberine and alkaloids research
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A chromosome-level genome assembly of the Chinese herbal medicine Chelidonium majus — Xialian Bu, Ai-Long Zheng, et al. · Scientific Data (2025) | TGRS Research Map | TGRS