Factors Predicting the Efficacy of Valbenazine and Exacerbation of Tardive Dyskinesia After Valbenazine Discontinuation in Japanese Patients

Although multiple regression analysis did not identify strong predictors of valbenazine efficacy and change in TD symptoms after valbenazine discontinuation, valbenazine dose was associated with meaningful improvement in TD. Rather than indicating efficacy in patients with specific factors, the data suggest a possible dose-dependent trend in improvement with valbenazine.

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Publication Details

Journal
Journal of Clinical Psychopharmacology
Published
2025-10-14
DOI
https://doi.org/10.1097/jcp.0000000000002092
Primary Topic
Parkinson's Disease Mechanisms and Treatments
Type
article
Field-Weighted Citation Impact
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article

Factors Predicting the Efficacy of Valbenazine and Exacerbation of Tardive Dyskinesia After Valbenazine Discontinuation in Japanese Patients

Hideaki Masui, Hiroyoshi Takeuchi, Yutaka Susuta, Yumi Watanabe
Journal of Clinical Psychopharmacology
Parkinson's Disease Mechanisms and Treatments
article

Factors Predicting the Efficacy of Valbenazine and Exacerbation of Tardive Dyskinesia After Valbenazine Discontinuation in Japanese Patients

Hideaki Masui, Hiroyoshi Takeuchi, Yutaka Susuta, Yumi Watanabe
article en

Abstract

Although multiple regression analysis did not identify strong predictors of valbenazine efficacy and change in TD symptoms after valbenazine discontinuation, valbenazine dose was associated with meaningful improvement in TD. Rather than indicating efficacy in patients with specific factors, the data suggest a possible dose-dependent trend in improvement with valbenazine.

Journal of Clinical PsychopharmacologyVol. 46(1)
Mitsubishi Corporation (United States) (US), Keio University (JP)
Openalex Percentile: Top 59%
Parkinson's Disease Mechanisms and Treatments
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