ISApl4, a New IS1595 Family Insertion Sequence Forming a Novel Pseudo-Compound Transposon That Confers Antimicrobial Multidrug Resistance in Actinobacillus pleuropneumoniae
This study identified the novel IS<i>Apl4</i> in porcine <i>A. pleuropneumoniae</i> and its association with the novel pseudo-compound transposon Tn<i>7560</i>, which proved to be an active element capable of disseminating multidrug resistance amongst <i>A. pleuropneumoniae</i>.
Authors
- Dennis Hanke (ORCID: https://orcid.org/0000-0002-3594-4234)
- Paul R. Langford (ORCID: https://orcid.org/0000-0002-6368-4724)
- Henrike Krüger-Haker
- Marc Stegger (ORCID: https://orcid.org/0000-0003-0321-1180)
- Janine T. Bossé (ORCID: https://orcid.org/0000-0002-8491-4779)
- Štefan Schwarz (ORCID: https://orcid.org/0000-0002-6303-8212)
- Søren Overballe‐Petersen (ORCID: https://orcid.org/0000-0002-1784-5128)
- Liza Miriam Cohen (ORCID: https://orcid.org/0000-0001-9077-7646)
- Yan-Wen Li (ORCID: https://orcid.org/0000-0002-4196-1751)
- Øystein Angen (ORCID: https://orcid.org/0000-0001-9690-5901)
Institutions
- Statens Serum Institut (DK)
- Murdoch University (AU)
- Imperial College London (GB)
- Norwegian University of Life Sciences (NO)
- Freie Universität Berlin (DE)
Publication Details
- Journal
- Antibiotics
- Published
- 2025-10-14
- DOI
- https://doi.org/10.3390/antibiotics14101021
- Primary Topic
- Bacteriophages and microbial interactions
- Type
- article
- Field-Weighted Citation Impact
- 0.00