Assessment of Meropenem Stability in Meropenem Admixtures Using 2 g Vials and Normal Saline Prepared Using addEASE ^® Connectors

These data demonstrated meropenem concentrations using 2 g vials diluted in 100 mL normal saline when prepared using addEASE connectors remained >90% of the initial concentration over 6 hours at room temperature. This supports extended infusion administration of meropenem per contemporary guidance when prepared using this methodology. Since this method allows storage of doses in automated dispensing cabinets and bedside preparation, this may streamline pharmacy workflows and potentially reduce time to administration.