Predictors of Treatment Response to Fecal Microbiota Transplantation in Irritable Bowel Syndrome: A Pilot Study
FMT appears to be a potentially effective treatment for moderate to severe IBS, with significant symptom relief and gut microbiota changes. Lower baseline abundances of <i>Roseburia</i> and <i>Subdoligranulum</i> and greater shifts of gut microbiome profile toward donor microbiota after FMT may predict favorable FMT response. Long-term follow-up is on the way to assessing the durability of these effects.
Authors
- Yonghoon Choi (ORCID: https://orcid.org/0000-0002-1331-969X)
- Hyemin Jo (ORCID: https://orcid.org/0009-0002-8829-2994)
- Ho-Kyoung Lee (ORCID: https://orcid.org/0000-0001-8490-2391)
- Cheol Min Shin (ORCID: https://orcid.org/0000-0003-2265-9845)
- Hyuk Yoon (ORCID: https://orcid.org/0000-0002-2657-0349)
- Jinju Choi (ORCID: https://orcid.org/0000-0002-0869-898X)
- Nayoung Kim (ORCID: https://orcid.org/0000-0002-9397-0406)
- Dong Ho Lee (ORCID: https://orcid.org/0000-0002-6376-410X)
- Young Soo Park (ORCID: https://orcid.org/0000-0003-1893-7726)
- Yu Kyung Jun (ORCID: https://orcid.org/0000-0002-4046-8578)
- Young Hoon Chang (ORCID: https://orcid.org/0000-0001-9221-0993)
Institutions
- Seoul National University (KR)
- Seoul National University Bundang Hospital (KR)
Publication Details
- Journal
- Journal of Neurogastroenterology and Motility
- Published
- 2025-10-13
- DOI
- https://doi.org/10.5056/jnm24183
- Citations
- 1
- Primary Topic
- Gastrointestinal motility and disorders
- Type
- article
- Field-Weighted Citation Impact
- 1.81