Investigating cefepime/taniborbactam for the treatment of complicated urinary tract infections

Cefepime/taniborbactam demonstrates promising <i>in vitro</i> activity against a broad range of β-lactamase-producing bacteria, such as carbapenemase-producing <i>Enterobacterales</i>, including those producing metallo-β-lactamases, and difficult-to-treat <i>Pseudomonas aeruginosa</i>. Its efficacy and safety profile in complicated urinary tract infections suggest that it could represent a valuable therapeutic option, particularly in settings with high prevalence of difficult-to-treat pathogens.

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Publication Details

Journal
Expert Opinion on Pharmacotherapy
Published
2025-10-13
DOI
https://doi.org/10.1080/14656566.2025.2574849
Primary Topic
Urinary Tract Infections Management
Type
article
Field-Weighted Citation Impact
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article

Investigating cefepime/taniborbactam for the treatment of complicated urinary tract infections

Matteo Bassetti, Daniele Roberto Giacobbe, Antonio Vena, Claudia Bartalucci et al.
Expert Opinion on Pharmacotherapy
Urinary Tract Infections Management
article

Investigating cefepime/taniborbactam for the treatment of complicated urinary tract infections

Matteo Bassetti, Daniele Roberto Giacobbe, Antonio Vena, Claudia Bartalucci, Marianna Giurco
article en

Abstract

Cefepime/taniborbactam demonstrates promising <i>in vitro</i> activity against a broad range of β-lactamase-producing bacteria, such as carbapenemase-producing <i>Enterobacterales</i>, including those producing metallo-β-lactamases, and difficult-to-treat <i>Pseudomonas aeruginosa</i>. Its efficacy and safety profile in complicated urinary tract infections suggest that it could represent a valuable therapeutic option, particularly in settings with high prevalence of difficult-to-treat pathogens.

Expert Opinion on PharmacotherapyVol. 26(14-15)
Ospedale Policlinico San Martino (IT), University of Genoa (IT)
Openalex Percentile: Top 61%
Urinary Tract Infections Management
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