Implementation of recommendations regarding pharmacotherapy optimization in patients with heart failure with reduced ejection fraction undergoing scheduled hospitalization: the HEROES study

In the Polish multicenter HEROES registry, over 80% of the patients with HFrEF were discharged on 4‑pillar GDMT. Nevertheless, the attainment of target high‑dose GDMT remained suboptimal. These findings provide new insights into the variability of GDMT implementation at the national level and underline the need for strategies to improve dosing optimization.

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Publication Details

Journal
Polskie Archiwum Medycyny Wewnętrznej
Published
2025-10-14
DOI
https://doi.org/10.20452/pamw.17135
Primary Topic
Pharmaceutical Practices and Patient Outcomes
Type
article
Field-Weighted Citation Impact
0.00

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article

Implementation of recommendations regarding pharmacotherapy optimization in patients with heart failure with reduced ejection fraction undergoing scheduled hospitalization: the HEROES study

Agnieszka Major, Dominika Klimczak‐Tomaniak, Przemysław Leszek, Katarzyna Byczkowska et al.
Polskie Archiwum Medycyny Wewnętrznej
Pharmaceutical Practices and Patient Outcomes
article

Implementation of recommendations regarding pharmacotherapy optimization in patients with heart failure with reduced ejection fraction undergoing scheduled hospitalization: the HEROES study

Agnieszka Major, Dominika Klimczak‐Tomaniak, Przemysław Leszek, Katarzyna Byczkowska, Piotr Hamala, Agata Galas, Michał Tkaczyszyn, Agata Tymińska, Robert Morawiec, Anna Furman-Niedziejko, Adrian Stefański, Paweł Krzesiński
article en

Abstract

In the Polish multicenter HEROES registry, over 80% of the patients with HFrEF were discharged on 4‑pillar GDMT. Nevertheless, the attainment of target high‑dose GDMT remained suboptimal. These findings provide new insights into the variability of GDMT implementation at the national level and underline the need for strategies to improve dosing optimization.

Polskie Archiwum Medycyny WewnętrznejVol. 135(11)
National Academy of Medicine (US), Jan Kochanowski University (PL), Medical University of Warsaw (PL), Wroclaw Medical University (PL), John Paul II Hospital (PL), Medical University of Lodz (PL), Institute of Cardiology (PL), Narodowy Instytut Leków (PL), Gdańsk Medical University (PL)
Polskiego Towarzystwa Kardiologicznego
Openalex Percentile: Top 65%
Pharmaceutical Practices and Patient Outcomes
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Implementation of recommendations regarding pharmacotherapy optimization in patients with heart failure with reduced ejection fraction undergoing scheduled hospitalization: the HEROES study — Agnieszka Major, Dominika Klimczak‐Tomaniak, et al. · Polskie Archiwum Medycyny Wewnętrznej (2025) | TGRS Research Map | TGRS