Natural Small-Molecule Bergapten Ameliorates Amyloid-β Pathology and Neuroinflammation in Alzheimer’s Disease

Our findings suggest that BG mitigates AD pathological features by suppressing MAPK-mediated neuroinflammation and represents a promising natural small molecule for the prevention and treatment of AD.

Authors

Jing Zhang (ORCID: https://orcid.org/0000-0002-2751-2036)
Jingyan Zhang (ORCID: https://orcid.org/0000-0002-2719-0866)

Institutions

Fujian Medical University (CN)

Publication Details

Journal: Nutrients
Published: 2025-10-14
DOI: https://doi.org/10.3390/nu17203218
Primary Topic: Alzheimer's disease research and treatments
Type: article
Field-Weighted Citation Impact: 0.00

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article

Natural Small-Molecule Bergapten Ameliorates Amyloid-β Pathology and Neuroinflammation in Alzheimer’s Disease

Jing Zhang, Jingyan Zhang

Oct 14, 2025

Nutrients

Alzheimer's disease research and treatments

article

Natural Small-Molecule Bergapten Ameliorates Amyloid-β Pathology and Neuroinflammation in Alzheimer’s Disease

Jing Zhang, Jingyan Zhang

October 14, 2025article en

Abstract

NutrientsVol. 17(20)

Fujian Medical University (CN)

Openalex Percentile: Top 64%

Alzheimer's disease research and treatments

DOI Open Access PDF OpenAlex

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Natural Small-Molecule Bergapten Ameliorates Amyloid-β Pathology and Neuroinflammation in Alzheimer’s Disease — Jing Zhang, Jingyan Zhang · Nutrients (2025) | TGRS Research Map | TGRS