Comparative analysis of treatments for vertebrogenic chronic low back pain: Intradiscal steroid injections vs. basivertebral nerve radiofrequency ablation
Vertebrogenic chronic low back pain (CLBP) significantly impairs the quality of life of patients, necessitating effective treatment strategies. The present study compared two intervention strategies for this condition: Intradiscal steroid injection (IDSI) in one group with 12 patients, vs. intraosseous basivertebral nerve radiofrequency ablation (BVA) in another group of 10 patients. The present study included patients aged 18-70 years, irrespective of sex, whilst specific inclusion and exclusion criteria were applied. IDSI involves corticosteroid injections into the intervertebral disc, reducing inflammation and pain, whereas BVA targets the basivertebral nerve to disrupt pain signals. A retrospective analysis of the Oswestry Disability Index (ODI) scores of the patients before and after treatment revealed that both treatments effectively reduce disability. The IDSI revealed a higher percentage of complete symptom resolution (at 75%), whereas BVA appeared to provide more consistent and notable improvements across patients, with complete symptom resolution at 70%. Despite potential side-effects, such as transient pain, increased blood sugar levels, nerve damage or infection, both treatments provide substantial pain relief and benefits that outweigh typical side-effects, presumably underscoring the importance of personalized treatment plans. Nonetheless, taking into consideration the notable limitations of the present study, it is essential to emphasize the requirement for further larger-scale research.
Authors
- Elias Vasiliadis (ORCID: https://orcid.org/0000-0003-2428-5250)
- Athanasios Galanis
- Vasileios Marougklianis
- Evangelos Sakellariou (ORCID: https://orcid.org/0000-0002-7262-0044)
- Meletis Rozis (ORCID: https://orcid.org/0000-0002-4688-3641)
- Evangelia Argyropoulou (ORCID: https://orcid.org/0000-0002-4849-2708)
- Andreas Morakis
- Angelos Kaspiris (ORCID: https://orcid.org/0000-0003-3265-5522)
- Dimitris Tzortzis
- Spyros G Pneumaticos
- Panagiotis Karampinas (ORCID: https://orcid.org/0000-0001-8475-5475)
- Nikolaos Parchas
Institutions
- National and Kapodistrian University of Athens (GR)
- General University Hospital of Patras (GR)
- KAT General Hospital of Attica (GR)
Publication Details
- Journal
- Medicine International
- Published
- 2025-10-14
- DOI
- https://doi.org/10.3892/mi.2025.275
- Primary Topic
- Spine and Intervertebral Disc Pathology
- Type
- article
- Field-Weighted Citation Impact
- 0.00