Compounds Influencing Magnesium Absorption

Magnesium (Mg2+) is the fourth most abundant cation in the body and the second most common at the Intracellular Level (IC). In humans, it is involved in the activity of hundreds of enzymes, covering approximately 80% of metabolic functions. Homeostasis is achieved by a balance between ingestion, excretion, and reservoir. According to data from Health and Nutrition Organizations, an important percentage of individuals consume less than the Dietary Reference Intake (DRI) of magnesium from food. In the intestine, there are several inhibitors and enhancers of magnesium absorption. This includes physicochemical and dietary factors. This narrative review aims to evaluate the compounds influencing Mg2+ absorption. These factors can be considered when determining Dietary Reference Intakes (DRIs) for the population to prevent deficiency and non-communicable diseases. The recommendations aim to increase fruit and vegetable consumption, as they are mineral-rich and alkalinizing foods.

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Publication Details

Journal
Nutrition & Food Science International journal
Published
2025-09-16
DOI
https://doi.org/10.19080/nfsij.2025.14.555895
Primary Topic
Magnesium in Health and Disease
Type
article
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article

Compounds Influencing Magnesium Absorption

Lusliany Josefina Rondón
Nutrition & Food Science International journal
Magnesium in Health and Disease
article

Compounds Influencing Magnesium Absorption

Lusliany Josefina Rondón
article en

Abstract

Magnesium (Mg2+) is the fourth most abundant cation in the body and the second most common at the Intracellular Level (IC). In humans, it is involved in the activity of hundreds of enzymes, covering approximately 80% of metabolic functions. Homeostasis is achieved by a balance between ingestion, excretion, and reservoir. According to data from Health and Nutrition Organizations, an important percentage of individuals consume less than the Dietary Reference Intake (DRI) of magnesium from food. In the intestine, there are several inhibitors and enhancers of magnesium absorption. This includes physicochemical and dietary factors. This narrative review aims to evaluate the compounds influencing Mg2+ absorption. These factors can be considered when determining Dietary Reference Intakes (DRIs) for the population to prevent deficiency and non-communicable diseases. The recommendations aim to increase fruit and vegetable consumption, as they are mineral-rich and alkalinizing foods.

Nutrition & Food Science International journalVol. 14(4)
Instituto Venezolano de Investigaciones Científicas (VE), Universidad Central de Venezuela (VE)
Openalex Percentile: Top 65%
Magnesium in Health and Disease
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