Cerebral Venous Thrombosis as a Complication of Spontaneous Intracranial Hypotension: A Case Report

Spontaneous intracranial hypotension (SIH) is an uncommon condition caused bycerebrospinal fluid (CSF) leakage, which can lead to complications such as cerebralvenous thrombosis (CVT), occurring in 1–2% of SIH patients. This case report describesthe presentation, diagnosis, and management of SIH complicated by CVT. A 36-year-oldwoman with no comorbidities presented with a three-week history of severe, initiallyorthostatic headaches. Neurological examination revealed mild bilateral disc oedema,and imaging showed generalized brain oedema. MRI with MRV confirmed cerebralvenous sinus thrombosis along with typical SIH features, including pachymeningealenhancement and venous engorgement. She was treated with heparin infusion andisotonic saline, responding well without seizures or hemorrhagic complications.This case highlights the risk of CVT in SIH and underscores the importance of earlydiagnosis through neuroimaging and lumbar puncture. The patient’s favorableresponse to anticoagulation demonstrates effective management, though furtherstudies are needed to establish definitive treatment guidelines for SIH-associated CVT.