Assessing the beneficial effect of Lactobacillus plantarum MS1 and Lactobacillus delbrueckii YN1 on colitis in a rat model
<i>Lactobacillus plantarum</i> MS1 and <i>Lactobacillus delbrueckii</i> YN1 have shown significant potential in alleviating AA-induced colitis symptoms. Their administration leads to a marked reduction in pro-inflammatory cytokines such as TNF-α, IL-17, and IL-6, while enhancing IL-10 levels, indicating their promise as therapeutic candidates for inflammatory bowel disease (IBD).
Authors
- Farzam Sheikhzadeh Hesari (ORCID: https://orcid.org/0000-0002-5945-7393)
- Mohammad Hossein Modarressi (ORCID: https://orcid.org/0000-0003-2763-1964)
- Gholamreza Zarrini (ORCID: https://orcid.org/0000-0002-1087-0769)
- Manizheh Hajizadeh Varzeghan
Institutions
- Islamic Azad University, Science and Research Branch (IR)
- University of Tehran (IR)
- University of Tabriz (IR)
Publication Details
- Journal
- Iranian Journal of Microbiology
- Published
- 2025-10-13
- DOI
- https://doi.org/10.18502/ijm.v17i5.19889
- Primary Topic
- Probiotics and Fermented Foods
- Type
- article
- Field-Weighted Citation Impact
- 0.00