Serological risk factors for steroid-induced osteonecrosis in HIV men: a Bayesian case–control study

Elevated triglycerides, FDP, and PTA significantly increase the risk of SONFH in HIV patients, while prolonged PT may be protective. These serum markers could guide early intervention, though larger prospective studies are needed.

Authors

Yunxiao Ji (ORCID: https://orcid.org/0009-0001-2862-4531)
Kangpeng Li (ORCID: https://orcid.org/0009-0008-8406-5990)
Qiang Zhang (ORCID: https://orcid.org/0000-0002-0091-5433)
Changsong Zhao (ORCID: https://orcid.org/0000-0001-5359-5106)
Rugang Zhao

Institutions

Capital Medical University (CN)
Peking University (CN)
Peking University Third Hospital (CN)
Beijing Ditan Hospital (CN)

Publication Details

Journal: Frontiers in Medicine
Published: 2025-10-14
DOI: https://doi.org/10.3389/fmed.2025.1650001
Primary Topic: Bone and Joint Diseases
Type: article
Field-Weighted Citation Impact: 0.00

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article

Serological risk factors for steroid-induced osteonecrosis in HIV men: a Bayesian case–control study

Yunxiao Ji, Kangpeng Li, Qiang Zhang, Changsong Zhao et al.

Oct 14, 2025

Frontiers in Medicine

Bone and Joint Diseases

article

Serological risk factors for steroid-induced osteonecrosis in HIV men: a Bayesian case–control study

Yunxiao Ji, Kangpeng Li, Qiang Zhang, Changsong Zhao, Rugang Zhao

October 14, 2025article en

Abstract

Elevated triglycerides, FDP, and PTA significantly increase the risk of SONFH in HIV patients, while prolonged PT may be protective. These serum markers could guide early intervention, though larger prospective studies are needed.

Frontiers in MedicineVol. 12

Capital Medical University (CN), Peking University (CN), Peking University Third Hospital (CN), Beijing Ditan Hospital (CN)

Openalex Percentile: Top 63%

Bone and Joint Diseases

DOI Open Access PDF OpenAlex

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Serological risk factors for steroid-induced osteonecrosis in HIV men: a Bayesian case–control study — Yunxiao Ji, Kangpeng Li, et al. · Frontiers in Medicine (2025) | TGRS Research Map | TGRS