Stage IA and IC adult granulosa cell tumors: Clinical features, long-term outcomes and prognostic factors in a 333-patient cohort over three decades
Unilateral salpingo-oophorectomy instead of simple cystectomy demonstrated a favorable safety profile in reproductive patients with stage I AGCT. Comprehensive surgical staging without lymphadenectomy should be considered as a viable treatment strategy, especially in the stage IC disease, manifesting a significantly higher recurrence rate and shorter DFS compared to stage IA counterparts.
Authors
- Dongyan Cao (ORCID: https://orcid.org/0000-0003-4253-832X)
- Xiao Ma (ORCID: https://orcid.org/0000-0001-9940-8468)
- Mei Yu
- Huimei Zhou (ORCID: https://orcid.org/0009-0008-5085-6110)
- Ying Cao (ORCID: https://orcid.org/0000-0002-8256-8497)
- Tao Wang (ORCID: https://orcid.org/0009-0005-2305-2449)
- Jingwen Gan
Institutions
- Chinese Academy of Medical Sciences & Peking Union Medical College (CN)
- Peking Union Medical College Hospital (CN)
Publication Details
- Journal
- International Journal of Clinical Oncology
- Published
- 2025-10-14
- DOI
- https://doi.org/10.1007/s10147-025-02897-w
- Primary Topic
- Ovarian cancer diagnosis and treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- China Postdoctoral Science Foundation