Hypokalemic Periodic Paralysis: A Case Report
Hypokalaemic periodic paralysis (HPP) is a rare neuromuscular disorder characterized by recurrent episodes of transient muscle weakness associated with hypokalaemia. The condition typically presents in childhood or adolescence. In this case, a 17-year-old male presented with acute-onset limb weakness upon waking. Examination revealed marked truncal and proximal muscle weakness with preserved distal strength. Serum potassium was 2.7 mmol/L. His symptoms fully resolved following intravenous potassium replacement. HPP is often underdiagnosed, and diagnostic delays can leave patients vulnerable to avoidable complications, including recurrent episodes and potentially life-threatening arrhythmias. This case highlights the importance of considering HPP in young patients presenting with acute muscle weakness and hypokalaemia.
Authors
- Zara Marchant
- Mohsin Wani
- Umed Nadir
Institutions
- Royal Hampshire County Hospital (GB)
- Hampshire Hospitals NHS Foundation Trust (GB)
Publication Details
- Journal
- Cureus
- Published
- 2025-10-14
- DOI
- https://doi.org/10.7759/cureus.94524
- Primary Topic
- Ion Transport and Channel Regulation
- Type
- article
- Field-Weighted Citation Impact
- 0.00