Immunomodulatory effects of probiotic Lactobacillus brevis ZG2488 on SARS-CoV-2 vaccine responses in mice
These findings demonstrate that L. brevis ZG2488 enhances the immune response to the SARS-CoV-2 vaccine through synergistic and multi-mechanistic actions, supporting its potential as a probiotic adjuvant strategy.
Authors
- Danna Pu
- Zhihong Ren (ORCID: https://orcid.org/0000-0001-8762-2600)
- Ji Pu (ORCID: https://orcid.org/0000-0003-2268-9796)
- Sihui Zhang (ORCID: https://orcid.org/0000-0001-9693-0728)
- Si‐Min Lu
- Yulu Chen (ORCID: https://orcid.org/0000-0003-2208-7242)
- Mengshan Chen
- Jing Yang (ORCID: https://orcid.org/0000-0003-4664-5528)
- Gui Zhang (ORCID: https://orcid.org/0000-0002-1123-7877)
- Jianguo Xu
- Zhijie Cao
Institutions
- Shanxi Medical University (CN)
- Chinese Academy of Medical Sciences & Peking Union Medical College (CN)
- Peking University (CN)
- Nankai University (CN)
- Shandong Provincial Hospital (CN)
- National Institute for Communicable Disease Control and Prevention (CN)
- Shandong First Medical University (CN)
Publication Details
- Journal
- Frontiers in Microbiology
- Published
- 2025-10-14
- DOI
- https://doi.org/10.3389/fmicb.2025.1655383
- Citations
- 1
- Primary Topic
- Probiotics and Fermented Foods
- Type
- article
- Field-Weighted Citation Impact
- 1.16
Funders
- Fudan University
- Chinese Center for Disease Control and Prevention
- Shanghai Medical College, Fudan University